Skip Navigation

Diabetes and Metabolic Disease

Researchers in white lab coats working with laboratory equipment.

Diabetes and Metabolic Disease

OU has established leadership in Diabetes through the Harold Hamm Diabetes Center and key departments in the College of Medicine. OU’s Diabetes efforts will have a  core mission in understanding, preventing, and treating diabetes and metabolic disease, conditions that represent some of the most pressing and costly health challenges facing Oklahoma and the nation.

Key hiring emphases include:

  • Molecular and cellular mechanisms of diabetes and metabolic dysfunction
  • Obesity biology and metabolic regulation
  • Autoimmune and microbiome-mediated disease pathways
  • Prevention science, lifestyle interventions, and community-based strategies
  • Complications affecting cardiovascular, renal, neurologic, and ocular systems
  • Precision therapeutics and pharmacogenomics

By linking basic discovery with clinical and population-level interventions, OU will advance scalable solutions to reduce disease burden and improve long-term outcomes.

About Harold Hamm Diabetes Center

OU Health Harold Hamm Diabetes Center has quickly emerged as one of the world’s top comprehensive centers of excellence for adults, young adults and children with all types of diabetes. Through novel research aimed at progress toward a cure for diabetes and its complications, dramatically improved patient care options, and programs aimed at preventing the spread of diabetes, the center is rapidly curtailing the impact of the world diabetes crisis.

Harold Hamm Diabetes Center.

Diabetes Research News

Research
October 26, 2026

Weight-loss surgery produces lasting diabetes remission, long-term study finds

People with type 2 diabetes were much more likely to achieve remission after weight-loss surgery than after intensive medical and lifestyle management, according to a long-term study. Researchers also identified patient characteristics linked to remission and to the likelihood of diabetes returning.


Research
October 19, 2026

OU diabetes researcher identifies potential new target for type 2 diabetes

A protein called Miro1 found at elevated levels in the skeletal muscle of people with type 2 diabetes may contribute to insulin resistance, potentially making it a target for future treatments that help the body regulate blood sugar, according to a study published today in Nature Communications.


Campus & Community
October 13, 2026

OU College of Medicine researcher named 2026 AAIP Physician of the Year

Dorothy A. Rhoades, M.D., M.P.H., has been recognized for her impact on improving Native American health outcomes. She was honored by the Association of American Indian Physicians at its 54th Annual Meeting & Health Conference.


Photo Gallery
September 23, 2026

A Game Changer: Harold Hamm commits largest gift in OU history

The University of Oklahoma announced an historic $150 million gift from Harold Hamm, the largest single gift in university history, to lift the health of Oklahoma.


Impact
September 22, 2026

A Game Changer: Harold Hamm commits largest gift in OU history to lift health of Oklahoma, name Health Campus

The University of Oklahoma today announced an historic $150 million gift from Harold Hamm, the largest single gift in university history, to lift the health of Oklahoma by advancing health education, research and discovery, strengthening the state’s health care workforce and accelerating the pursuit of breakthroughs against Oklahoma’s critical public health challenges.


Research
July 30, 2026

OU Researcher Joins $12 Million Effort to Advance Obesity Drug Discovery

A University of Oklahoma researcher is part of an international team developing a new way to discover obesity drugs using human cells instead of animal models, an approach that could speed the development of more effective and affordable treatments. The effort is supported by a $12 million grant from the Novo Nordisk Foundation.


Research
April 01, 2026

Researchers Identify Mechanism for Body Weight-Reducing Hormone

New research from University of Oklahoma researchers, published in Cell Reports, reveals that a hormone that reverses obesity in mice appears to work by signaling to a brain region involved in metabolism and appetite regulation, the same area targeted by the popular GLP-1 drugs.


Research
January 14, 2026

Maternal Microbiome Compound May Hold Key to Preventing Liver Disease

New research from the University of Oklahoma has found that supplementing pregnant and lactating mice with a naturally occurring compound produced by healthy gut bacteria significantly lowered rates of fatty liver disease in their offspring as they aged.


Impact
October 27, 2025

Gala Raises $4.7 Million for OU Health Harold Hamm Diabetes Center

More than 800 people attended the 2025 Connect+Cure Gala on Wednesday night, raising $4.7 million to support research and programs at the University of Oklahoma Health Harold Hamm Diabetes Center.


Campus & Community
July 21, 2025

Cui Brings Neuroscience Expertise to Harold Hamm Diabetes Center

In June, Huxing Cui, Ph.D., joined the OU Health Harold Hamm Diabetes Center as associate professor in the OU College of Medicine, Department of Cell Biology. Prior to joining the OU Health campus, Cui was most recently an associate professor of neuroscience and pharmacology at the University of Iowa.