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Kaili Liu

Interlocking OU, Gallogly College of Engineering, Peggy and Charles Stephenson School of Biomedical Engineering, The University of Oklahoma website wordmark.

Kaili Liu

Kaili Liu

Research Assistant Professor

Email: kaili-liu@ou.edu
Office: Gallogly Hall 406

Education

Ph.D. Biochemistry and Molecular Biology
Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

B.S. Biological Sciences
Nanjing Agricultural University, Nanjing, China

Research Focus

  • Local intervention-based cancer immunotherapy
  • Single-cell sequencing and analysis in cancer therapy
  • Multi-omics studies for cancer therapy and vaccine development
  • K. Liu, A.R. Hoover, L. Wang, Y. Sun, T.I. Valerio, C. Furrer, J. Adams, J. Yang, M. Li, W.R. Chen, Localized ablative immunotherapy enhances antitumor immunity by modulating the transcriptome of tumor-infiltrating Gamma delta T cells, Cancer Letters, 604 (2024) 217267.
  • A.R. Hoover, K. Liu, C. Furrer, S.S.K. Lam, D.W. Anderson, Z. Zhou, J. Yang, C.F. Wong, A.D. Medcalf, X.-H. Sun, T. Hode, L. Alleruzzo, A. Delawder, J. Raker, G. Abousleiman, T.I. Valerio, Y. Sun, J.F. Papin, M. Li, W.R. Chen, N-Dihydrogalactochitosan Drives Conventional and Alternative Activations of STING to Synergize Type I IFN and IL-1β Productions for Antitumor Immunity, Advanced Functional Materials, n/a  2410079.
  • L. Wang, V. Sheth, K. Liu, P. Panja, A.N. Frickenstein, Y. He, W. Yang, A.G. Thomas, M.H. Jamei, J. Park, S. Lyu, N.D. Donahue, W.R. Chen, R. Bhattacharya, P. Mukherjee, S. Wilhelm, Primary Human Breast Cancer-Associated Endothelial Cells Favor Interactions with Nanomedicines, Advanced Materials, 36 (2024) 2403986.
  • J. Hu, K. Liu, C. Ghosh, T.P. Khaket, H. Shih, E. Kebebew, Anaplastic thyroid cancer spheroids as preclinical models to test therapeutics, Journal of Experimental & Clinical Cancer Research, 43 (2024) 85.
  • Hoover AR, More S, Liu K, West CL, Valerio TI, Furrer CL, Adams JP, Yu N, Villalva C, Kumar A, Alleruzzo L, Lam SSK, Hode T, Papin JF and Chen WR. N-dihydrogalactochitosan serves as an effective mucosal adjuvant for intranasal vaccine in combination with recombinant viral proteins against respiratory infection. Acta Biomaterialia. 2024; 175:279-292.
  • Hoover, A.R., Liu, K., DeVette, C.I., Krawic, J.R., Medcalf, A.D., West, C.L., Hode, T., Lam, S.S.K., Welm, A.L., Sun, X.-H., et al. (2022). Single-cell RNA sequencing reveals localized tumour ablation and intratumoural immunostimulant delivery potentiate T cell mediated tumour killing. Clinical and Translational Medicine 12, e937.
  • Bajana, S., Pankow, A., Liu, K., Michniowska, M., Urban, J.F., Chen, W.R., and Sun, X.-H. (2022). Correlation between circulating innate lymphoid cell precursors and thymic function. iScience, 103732. https://doi.org/10.1016/j.isci.2022.103732.
  • Liu K, Hoover AR, Krawic JR, DeVette CI, Sun XH, Hildebrand WH, Lang ML, Axtell RC, Chen WR. Antigen presentation and interferon signatures in B cells driven by localized ablative cancer immunotherapy correlate with extended survival. Theranostics 2022; 12(2):639-656. doi:10.7150/thno.65773.
  • Wang M, Li Y, Wang M, Liu K, Hoover AR, Li M, Towner RA, Mukherjee P, Zhou F, Qu J, Chen WR. Synergistic interventional photothermal therapy and immunotherapy using an iron oxide nanoplatform for the treatment of pancreatic cancer. Acta Biomater. 2021 Oct 30:S1742-7061(21)00716-9. doi: 10.1016/j.actbio.2021.10.048. Epub ahead of print. PMID: 34757232.
  • Hoover, Ashley R., Liu, Kaili and Chen, Wei R.. "Balance and modulation of immunoediting for cancer treatment using synergistic nano-photo-immuno effects" Nanophotonics, vol. 10, no. 12, 2021, pp. 3383-3389. https://doi.org/10.1515/nanoph-2021-0390
  • Hoover, Ashley R., Liu, Kaili, Valerio, Trisha I., Li, Min, Mukherjee, Priyabrata and Chen, Wei R.. "Nano-ablative immunotherapy for cancer treatment" Nanophotonics, vol. 10, no. 12, 2021, pp. 3247-3266. https://doi.org/10.1515/nanoph-2021-0171
  • Yan G, Shi L, Zhang F, Luo M, Zhang G, Liu P, Liu K, Chen WR, Wang X. Transcriptomic analysis of mechanism of melanoma cell death induced by photothermal therapy. J Biophotonics. 2021 Mar 17:e202100034. doi: 10.1002/jbio.202100034. Epub ahead of print. PMID: 33729683.
  • Wang, M., Rao, J., Wang, M., Li, X., Liu, K., Naylor, M. F., Nordquist, R. E., Chen, W. R., & Zhou, F. (2021). Cancer photo-immunotherapy: from bench to bedside. Theranostics, 11(5), 2218–2231. https://doi.org/10.7150/thno.53056
  • Wang CY, Chang CY, Wang CY, Liu K, Kang CY, Lee YJ, Chen WR. N-Dihydrogalactochitosan Potentiates the Radiosensitivity of Liver Metastatic Tumor Cells Originated from Murine Breast Tumors. International Journal of Molecular Sciences 2019, 20(22): 5581.
  • West C, Doughty A, Liu K, Chen WR. Monitoring tissue temperature during photothermal therapy for cancer. Journal of Bio-X Research 2019 Dec 2(4): 159-168. doi: 10.1097/JBR.0000000000000050
  • Yao Q, Wang L, Mittal R, Yan D, Richmond MT, Denyer S, Requena T, Liu K, Varshney GK, Lu Z, Liu X. Transcriptomic Analyses of Inner Ear Sensory Epithelia in Zebrafish. Anat Rec (Hoboken) 2019 Dec 28. doi: 10.1002/ar.24331.
  • Liu K, Petree C, Requena T, Varshney P, Varshney GK. Expanding the CRISPR Toolbox in zebrafish for studying development and disease. Front Cell Dev Biol 2019, 7:13.
  • Liu K, He Y, Yu L, Chen Y, He R. Markedly elevated formaldehyde in the cecum of APP/PS1 transgenic mouse model of Alzheimer's disease. Microbiol China 2017, 44(8): 1761-1766.
  • Liu KL, Wang XM, Li ZL, He RQ, Liu Y. In situ hybridization and immunostaining of Xenopus brain. Methods Mol Biol 2014, 1082:129-41.
  • Sun P, Chen JY, Li J, Sun MR, Mo WC, Liu KL, Meng YY, Liu Y, Wang F, He RQ, Hua Q. The protective effect of geniposide on human neuroblastoma cells in the presence of formaldehyde. BMC Complement Altern Med 2013, 13:152.
  • Liu K, Liu Y, Mo W, Qiu R, Wang X, Wu JY, He R. MiR-124 regulates early neurogenesis in the optic vesicle and forebrain, targeting NeuroD1. Nucleic Acids Res 2011, 39:2869-2879.
  • Qiu R, Liu K, Liu Y, Mo W, Flynt AS, Patton JG, Kar A, Wu JY, He R. The role of miR-124a in early development of the Xenopus eye. Mech Dev 2009, 126:804-816.
  • Qiu R, Liu Y, Wu JY, Liu K, Mo W, He R. Misexpression of miR-196a induces eye anomaly in Xenopus laevis. Brain Res Bull 2009, 79:26-31.
  • Liu KL, Xu S, Xuan W, Ling TF, Cao Z, Huang BK, Sun YG, Fang L, Liu ZY, Zhao N, et al. Carbon monoxide counteracts the inhibition of seed germination and alleviates oxidative damage caused by salt stress in Oryza sativa. Plant Science 2007, 172:544-555.
  • Xie Y, Ling T, Han Y, Liu K, Zheng Q, Huang L, Yuan X, He Z, Hu B, Fang L, et al. Carbon monoxide enhances salt tolerance by nitric oxide-mediated maintenance of ion homeostasis and up-regulation of antioxidant defence in wheat seedling roots. Plant Cell Environ 2008, 31:1864-1881.
  • Huang BK, Xu S, Xuan W, Li M, Cao ZY, Liu KL, Ling TF, Shen WB. Carbon monoxide alleviates salt-induced oxidative damage in wheat seedling leaves. Journal of Integrative Plant Biology 2006, 48:249-254.
  • Liu KL, Han HR, Xu YJ, Ling TF, Liu ZB, Sun YG, Hua R, Shen WB. (2005) Exogenous nitric oxide alleviates salt stress-induced membrane lipid peroxidation in rice seedling roots. Chinese J Rice Sci (in Chinese with English abstract), 19, 333-337

A complete list of publications available in Google Scholar.

Stephenson School of Biomedical Engineering
Gallogly Hall, Room 101
173 Felgar St. | Norman, OK 73019
Updated 3/6/2025 by Stephenson School of Biomedical Engineering: biomedical@ou.edu