Rupa Haldavnekar

Assistant Professor

Email: rupa@ou.edu
Phone: (405) 325-5390
Office: Engineering Lab 143
Office Hours: Tuesday 12:00-1:00pm,
Wednesday 11:30am-1:00pm, and
Thursday 12:00-1:00pm, or
by appointment

Education
Ph.D., Biomedical Engineering (2022)
Toronto Metropolitan University, Canada
MBA, Management
University of Pune, India
BEng., Mechanical Engineering
University of Pune, India

Research Focus

Optical liquid biopsy of cancer
Nano Biophotonics
Biomedical Engineering
Nanotechnology
Liquid Biopsy
Biomolcular/Cellular Spectroscopy
Machine Learning and Deep Learning

Courses Taught

Statics
Thermodynamics
Process Analytical Technologies and Data Science
Transport Phenomenon in Biological Systems I & II
Intro to Engineering Mechanics for Bioengineers

Recent Publications

Ishwar D, Ganesh, S., Haldavnekar, R., Venkatakrishnan, K., Tan, B. "Degradable Intracellular Self-Functionalized Nanoprobes for in-vitro Monitoring of Cancer" (2023) Materials Today Chemistry, 27, 101310. (IF 8.3)
Anish Verma, Rupa Haldavnekar, Krishnan Venkatakrishnan, Bo Tan “Dual-purpose 3D- Silica Nanostructure Matrix for Rapid Epigenetic Reprogramming of Tumor Cell to Cancer Stem Cell Spheroid" Small Methods (2023) 202200798, (IF: 15.367)
Haldavnekar, R., Venkatakrishnan, K. & Tan, B. (2020) “Next generation SERS- atomic scale platform for molecular level detection, Applied Materials Today 18 (2020) (First Author IF 10.04)
Haldavnekar, R., Venkatakrishnan, K. & Tan, B. (2020) “Functionalized, Complementary Live-Charge Quantum Surface-Enhanced Raman Scattering Probes for Biomolecular Detection” 3 (7) ACS Applied Nano Materials, 6945-6961, (First Author IF 6.140)
Haldavnekar, R., Vijayakumar, Sivaprasad Chinnakkannu, Venkatakrishnan, K. & Tan, B. (2021) “Prediction of Cancer Stem Cell Fate by Surface-Enhanced Raman Scattering Functionalized Nanoprobes” 14(11) ACS Nano (First Author IF 18.03)
Haldavnekar, R., Venkatakrishnan, K. & Tan, B. (2021) “Boosting the sub-cellular biomolecular cancer signals by self-functionalized tag-free nano sensor190, 113407, Biosensors and Bioelectronics, (First Author IF 10.26)
Haldavnekar, R; Venkatakrishnan, A; Kiani, A (2022) "Tracking the Evolution of Metastasis with Self-Functionalized 3D Nano Probes" ACS Appl. Bio Mater. 5, 4, 1633–1647, https://10.1021/acsabm.2c00043 (First Author IF 4.9)
Haldavnekar, R., Ganesh, S., Venkatakrishnan, K. & Tan, B. (2022) “Cancer Stem Cell DNA Enabled Real-Time Genotyping with Self-Functionalized Quantum Superstructures- Overcoming the Barriers of Non-Invasive cfDNA Cancer Diagnostics.” Small Methods, https://10.1002/smtd.202101467 (First Author IF: 15.367)
Dhinakaran, A., Ganesh S, Haldavnekar, R., Venkatakrishnan, K., Tan, B. & Das, S. (2022) “Holistic Analysis of Glioblastoma Stem Cell DNA Using Nanoengineered Plasmonic Metasensor for Glioblastoma Diagnosis.” Small Methods, https://10.1002/smtd.202200547. (IF: 15.367)
Tan, B., Ganesh, S., Haldavnekar, R., Venkatakrishnan, K. & (2022)”OncoProfiler – A Multi-Cancer Early Detection (MCED) Assay”, 21st Century Pathology, Volume 2(5), 128.
D Ishwar, K Venkatakrishnan, B Tan, R Haldavnekar (2023), “DNA Methylation Signatures of Tumor-Associated Natural Killer Cells with Self-Functionalized Nanosensor Enabled Colorectal Cancer Diagnosis”, Nano Letters, 2023, 23, 10, 4142–4151
Premachandran, S. *, Haldavnekar, R. *, Ganesh S, Venkatakrishnan, K., Tan, B. & Das, S. “Self-Functionalized Superlattice Nano Sensor Enables Glioblastoma Diagnosis Using Liquid Biopsy” 2023 ACS Nano 10.1021/acsnano.3c04118 (First Co-Author IF: 18.03)
Ishwar D*, Haldavnekar, R. *, Venkatakrishnan, K., Das, S., Tan, B. (2022) “Glioblastoma Associated Natural Killer Cell EVs Generating Tumour-Specific Signatures: Non-invasive GBM Liquid Biopsy with Self-Functionalized Quantum Probes.” ACS Nano, 16, 7, 10859–10877, https://10.1021/acsnano.2c03055 (First Co-Author IF 18.03)
Premachandran, S*., Haldavnekar, R.*, Venkatakrishnan, K., Tan, B. & Das, S. (2022) “DEEP Surveillance of Brain Cancer Using Self-Functionalized 3D Nanoprobes for Noninvasive Liquid Biopsy” ACS Nano, https://10.1021/acsnano.2c04187 (First Co-Author IF 18.03)
Ishwar D*, Haldavnekar, R.*, Venkatakrishnan, K., Tan, B. (2022) “Minimally invasive detection of cancer using metabolic changes in tumor-associated natural killer cells with Oncoimmune probes.” Nature Communications, 13, 4527. https://10.1038/s41467-022-32308-x (First Co-Author IF 17.69)
Haldavnekar, R, Venkatakrishnan, K, Tan, B (2022) “Cancer Stem Cell Derived Extracellular Vesicles with Self-Functionalized 3D Nano Sensor for Real-Time Cancer Diagnosis - Eliminating the Roadblocks in Liquid Biopsy”, ACS Nano, https://10.1021/acsnano.2c02971 (First Author IF 18.03)
Haldavnekar, R., Venkatakrishnan, K. & Tan, B. (2018) “Non Plasmonic Semiconductor Quantum SERS Probe as A Pathway For In Vitro Cancer Detection”, Nature Communications 9 (2018) (First Author, IF 17.69)