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Medical Imaging COBRE

OU Gallogly College of Engineering, Oklahoma COBRE in Cancer Imaging Research, The University of Oklahoma website wordmark
Oklahoma Center of Medical Imaging for Translational Cancer Research

Oklahoma Center of Medical Imaging for Translational Cancer Research

The objective of this COBRE is to establish a new biomedical imaging research center with appropriate infrastructure and research capacity along with a multidisciplinary mentoring team to support the promising research project leaders of junior investigators as they conduct innovative translational cancer research projects. The success of COBRE will ultimately have a high research and clinical impact, leading to a reduced cancer burden both for individual patients and society. 

Mission

This COBRE aims to enhance the capability of conducting multidisciplinary medical imaging technology and informatics-related translational cancer research on both the OU Norman and OUHSC campuses.

Vision

Promoting close and effective collaboration between biomedical engineering researchers and physician scientists on two OU campuses can significantly increase the efficacy and translational clinical impact of research projects.


Research Themes

In order to improve cancer detection and diagnosis accuracy and/or treatment efficacy using medical imaging and informatics technology, the research topics of the COBRE include but are not limited to:

  • Develop novel investigative medical imaging modalities and technologies to more sensitively detect tumors and monitor tumor response to treatment.
  • Identify and develop new quantitative imaging markers using advanced image processing and AI-based technology.
  • Assess the efficacy of the investigative cancer therapy drugs or procedures using medical imaging methods.
  • Develop new machine learning (ML) based prediction models that fuse both imaging and genomic biomarkers.

 


COBRE News


COBRE Cancer Imaging - Call for RPL Applications - 2025

  • We’re thrilled to announce another exciting funding opportunity!  The Oklahoma Center of Medical Imaging for Translational Cancer Research plan to submit a competitive renewal COBRE Phase 2 grant application in May 2025, with the goal of further enhancing local research capabilities in Medical Imaging and Translational Cancer Research. In accordance with NIH COBRE guidelines, we intend to select 4-5 new Research Project Leaders (RPLs) for our competitive renewal COBRE Phase 2 grant application. Each RPL will propose a research project that aligns with the COBRE common research theme. 
  • Full-time faculty members from any academic unit on the OU Norman and OUHSC campuses are eligible to apply by meeting the detailed criteria. The application submission deadline is November 15, 2024.

Please find the attached flyer and website link for detailed information:   


COBRE funding opportunity for Pilot Project Grants applications

  • We have exciting news about a funding opportunity! The Oklahoma Center of Medical Imaging for Translational Cancer Research (NIH - P20GM135009) is inviting applications for Pilot Project Grants. This program aims to provide seed funding to help researchers test new hypotheses and generate preliminary data for future extramural research grant applications.
  • Proposals should align with the central research theme of this COBRE, which focuses on translational biomedical imaging science research aimed at improving cancer detection, diagnosis accuracy, or treatment efficacy. This can be achieved by developing and/or applying novel medical imaging techniques (e.g., new investigative imaging systems/tools or procedures) or quantitative imaging markers (e.g., generated using advanced machine learning or artificial intelligence algorithms). All types of studies using retrospective human subject image data, vertebrate animal models, cancer cell line models, and/or dedicated imaging phantoms are accepted.
  • Full-time faculty members from any academic unit on the OU Norman and OUHSC campuses are eligible to apply by meeting the detailed criteria. The application submission deadline is November 15, 2024, and the anticipated project start date is January 1, 2025. Pilot Projects will be awarded at a level of $60,000 in direct costs per year, with each award lasting one year (12 months).

Please find the attached flyer for detailed information:


Publications and News Report in 2024

  • 08/2024-A study published in the July/September 2024 issue of Biophotonics Discovery explores the use of integrated multispectral autofluorescence imaging endoscopy combined with machine learning to automatically distinguish between benign and cancerous or pre-cancerous oral lesio (Dr. Javier Jo Team).
  • 08/2024- A paper published on Communications Engineering for automatic renal carcinoma biopsy guidance using forward-viewing endoscopic optical coherence tomography and deep learning (Dr. Qinggong Tang Team)
  • 07/2024– Dr. Tang co-authored a paper on Cell Cycle reporting on the synthesis and validation of a 37 amino acid RSPO1-mimetic peptide for interoperative imaging of colorectal cancer peritoneal metastatic disease.(Dr. Qinggong Tang Team)
  • 05/2024, A new study conducted by the Wilhelm Lab as "Study Reveals Promising Development in Cancer-Fighting Nanotechnologies


March 22, 2022
  • $11.3 Million Federal Grant Establishes New Center for Cancer Research at OU

Under the collaboration and support from Gallogly College of Engineering and Stephenson Cancer Center, a new Oklahoma Center of Medical Imaging for Translational Cancer Research will be established at OU.

Read the full story.


Publication Acknowledge COBRE Support

How to Acknowledge COBRE Support

Research reported in this [publication, release] is supported in part by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences, the National Institutes of Health, under grant number P20 GM135009.

Stephenson Research and Technology Center
Gallogly Hall of Biomedical Engineering

Contact Information

Administration Office Address:

Stephenson Research and Technology Center

101 David L. Boren Blvd, Rm 1160

Norman, OK 73019